Physiologic Therapy in Respiratory Diseases

Physiologic therapy in diseases of the respiratory system.

Inhaled Antibiotic Therapy in Chronic Respiratory Diseases

The management of patients with chronic respiratory diseases affected by difficult to treat infections has become a challenge in clinical practice. Conditions such as cystic fibrosis (CF) and non-CF bronchiectasis require extensive treatment strategies to deal with multidrug resistant pathogens that include Pseudomonas aeruginosa, Methicillin-resistant Staphylococcus aureus, Burkholderia specie...

Nanoparticle-based therapy for respiratory diseases.

Nanotechnology is an emerging science with the potential to create new materials and strategies involving manipulation of matter at the nanometer scale (<100 nm). With size-dependent properties, nanoparticles have introduced a new paradigm in pharmacotherapy - the possibility of cell-targeted drug delivery with minimal systemic side effects and toxicity. The present review provides a summary of...

An Update on Anti-IgE Therapy in Pediatric Respiratory Diseases

Anti-IgE treatment represents a major breakthrough in the therapeutic management of severe allergic asthma. Omalizumab is the unique biologic treatment registered for asthma therapy in children. The clinical efficacy and safety of omalizumab treatment in the pediatric population has been extensively documented in specific trials and consistently expanded from real-life studies. In addition, new...

The physiologic basis of high-altitude diseases.

Many physicians are surprised to learn how many people live, work, and play at high altitude. Some 140 million persons reside at altitudes over 2500 m, mainly in North, Central, and South America; Asia; and eastern Africa (1). Increasingly, people are moving to work at high altitude. For example, there are telescopes at altitudes over 5000 m (2) and mines at over 4500 m (3), and the Golmud–Lhas...